From North Howard Street in the west and southwest, the flames spread north through the retail shopping area as far as Fayette Street and began moving eastward, pushed by the prevailing winds. Narrowly missing the new 1900 Circuit Courthouse, now the Clarence M. Mitchell Jr. Courthouse, fire passed the historic Battle Monument Square from 1815 to 1827 at North Calvert Street, and the quarter-century-old Baltimore City Hall, built in 1875 on Holliday Street; and finally spread further east to the Jones Falls stream which divided the downtown business district from the old East Baltimore tightly-packed residential neighborhoods of Jonestown (also known as Old Town) and newly named "Little Italy". The fire's wide swath burned as far south as the wharves and piers lining the north side of the old "Basin" (today's "Inner Harbor") of the Northwest Branch of the Baltimore Harbor and Patapsco River facing along Pratt Street.
The Great Baltimore Fire raged in Baltimore, Maryland from Sunday February 7 to Monday February 8, 1904. More than 1,500 buildings were completely leveled, and some 1,000 severely damaged, bringing property loss from the disaster to an estimated $100 million. 1,231 firefighters helped bring the blaze under control, both professional paid truck and engine companies from the Baltimore City Fire Department (B.C.F.D.) and volunteers from surrounding counties and outlying towns, as well as out-of-state units that arrived on the major railroads. The fire destroyed much of central Baltimore, including over 1,500 buildings covering an area of some 140 acres (57 ha).
It is considered the third worst conflagration in an American city, surpassed only by the Great Chicago Fire of 1871, and the San Francisco Earthquake and Fire of 1906.
—Wikipedia